npj_Systems Biology and Applications


  • Nozomu Yachie; Robotic Biology Consortium; Tohru Natsume. Robotic crowd biology with Maholo LabDroids. Nature Biotechnology. 35, 4, 310-312, April 2017.
  • Gregory J. Baker, P.S. Thiagarajan, Sucheendra K. Palaniappan, Stephanie H. Davis, Jodene K. Moore and Peter K. Sorger; A flow-based immunoprofiling strategy for interrogating system-wide leukocyte composition in response to glioblastoma; Cancer Res July 1 2017 (77) (13 Supplement) 1678; DOI: 10.1158/1538-7445.AM2017-1678
  • Caron, E., Roncagalli, R., Hase, T., Wolski, W.E., Choi, M., Menoita,M.G., Durand, S., García-Blesa, A., Fierro-Monti, I., Sajic, T., Heusel, M., Weiss, T., Malissen, M.,Schlapbach, R., Collins, B.C., Ghosh, S., Kitano, H., Aebersold, R., Malissen, B., Precise Temporal Profiling of Signaling Complexes in Primary Cells Using SWATH Mass Spectrometry. Cell Reports 18, 3219–3226 (2017).
  • Takeshi Hase, Samik Ghosh, Sucheendra K. Palaniappan, and Hiroaki Kitano (Chapter 13. Cancer Network Medicine), Network Medicine - Complex Systems in Human Disease and Therapeutics (Joseph Loscalzo, Albert-László Barabási, and Edwin K. Silverman (Eds.)), Harvard University Press 2017 ISBN 9780674436534
  • Sucheendra K. Palaniappan, Francois Bertaux, Matthieu Pichené, Gregory Batt, Eric Fabre and Blaise Genest. Abstracting Biological Pathways using Information theory measures: A case study of Apoptosis Pathway. February 2017, Oxford Bioinformatics 
  • Kitano, H. Biological Complexity and the need for Computational Approaches. Philosophy of Systems Biology: Perspectives from Scientists and Philosophers (Sara Green ed., Springer), 169-180, Mar. 21, 2017. (book chapter)










*Please also check publication list ( for extensive list of the publications up to 2007.





  • Kitano, H., Oda, K., Kimura, T., Matsuoka, Y., Csete, M., Doyle, J., Muramatsu, M.. Metabolic Syndrome and Robustness Tradeoffs, Diabetes 53, S6-S15, 2004 PFD file
  • Kitano, H.. Biological Robustness. Nature Review Genetics. 5, 826-837, 2004 PDF file
  • Oda, K.; Kimura, T, Matsuoka, Y.; Funahashi, A.; Muramatsu, M.; Kitano, H. Molecular Interaction Map of Macrophage. AfCS Report. 2004. PDF file
  • M. Hucka; A. Finney; B.J. Bornstein; S.M. Keating; B.E. Shapiro; J. Matthews; B.L. Kovitz; M.J. Schilstra; A. Funahashi; J.C. Doyle; and H. Kitano Evolving a lingua franca and associated software infrastructure for computational systems biology: theSystemsBiologyMarkupLanguage(SBML) project. IEE Systems Biology. 1:41-53, 2004
  • Kitano, H. Cancer as a robust system: implications for anticancer therapy. Nature Reviews Cancer 4:227-235, 2004. Abstract..



  • Kitano, H. Systems Biology: A Brief Overview. Science. 295, 1662-1664, 2002. Abstract...
  • Kitano, H. Computational Systems Biology. Nature. 420, 206-210, 2002. Abstract...
  • Kitano, H. Standards for modeling. Nat. Biotech. 20, 337, 2002. Abstract...
  • Hucka, M., Finney, A., Sauro, H. M., Bolouri, H., Doyle, J., and Kitano,H. The ERATO Systems Biology Workbench: enabling interaction and exchange between software tools for computational biology. Proc. Pac Symp Biocomput. 2002, 450-61, 2002. Abstract...
  • Kitano, H. Looking beyond the details: a rise in system-oriented approaches in genetics and molecular biology.
    Curr Genet. 41, 1-10, 2002. Abstract...
  • Morohashi, M., Winn, A. E., Borisuk, M. T., Bolouri, H., Doyle, J., and Kitano, H. Robustness as a measure of plausibility in models of biochemical networks. J. Theor. Biol. 216, 19-30, 2002. Abstract...


  • Kyoda, K. M., Morohashi, M., Onami, S., and Kitano, H. A gene network inference method from continuous-value gene expression data of wild-type and mutants. Genome Informatics. 11, 196-204, 2000. Abstract...

*Please also check publication list ( for extensive list of the publication upto 2007.

npj_Systems Biology and Applications